"Nor does she perform anything by means of angelic invocations, or by incantations, or by any other wicked curious art; but, directing her prayers to the Lord, who made all things, in a pure, sincere, and straightforward spirit, and calling upon the name of our Lord Jesus Christ, she has been accustomed to work miracles for the advantage of mankind, and not to lead them into error” (Irenaeus, Against Heresies, Book II, Chap. 32).
“We judge it improper to pray to those beings who themselves offer up prayers (to God), seeing even they themselves would prefer that we should send up our requests to the God to whom they pray, rather than send them downwards to themselves, or apportion our power of prayer between God and them.” (Origen, Against Celsus, Book V, Chap. XI)
“It is manifest that those who either make prayers to the dead, or venerate the earth, or make over their souls to unclean spirits, do not act as becomes men, and that they will suffer punishment for their impiety and guilt, who, rebelling against God, the Father of the human race, have undertaken inexpiable rites, and violated every sacred law.” (Lactantius, Divine Institutes 2:18)
"If Christ is only man, why is a man invoked in prayers as a Mediator, when the invocation of a man to afford salvation is condemned as ineffectual? If Christ is only man, why is hope rested upon Him, when hope in man is declared to be accursed?" (Novatian)
"No one, for instance, would pray to receive from God and the Angels, or from any other creature, nor would any one say, 'May God and the Angel give you;' but from Father and the Son, because of their oneness and the oneness of Their giving" (Athanasius, Against the Arians)